Chapter 1: Introduction.

Chapter 2: History, definition and diagnosis of the metabolicSyndrome.

Chapter 3: Insulin resistance in the metabolic syndrome.

Chapter 4: Is it necessary to redefine the metabolicsyndrome?

Chapter 5: Is insulin resistance a disorder of the brain?

Chapter 6: Obesity.

Chapter 7: Perinatal nutrition and obesity.

Chapter 8: Essential hypertension.

Chapter 9: Dietary factors and hypertension.

Chapter 10: Is hypertension a disorder of the brain?

Chapter 11: Type 2 diabetes mellitus.

Chapter 12: Pathophysiology of type 2 diabetes mellitus withparticular reference to hypothalamus.

Chapter 13: Insulin and insulin receptors in the brain and theirrole in the pathogenesis of obesity and type 2 diabetesmellitus.

Chapter 14: Insulin, endothelial nitric oxide and the metabolicsyndrome.

Chapter 15: Obesity, type 2 diabetes mellitus and the metabolicsyndrome and the gut microbiota.

Chapter 16: Is it possible that the metabolic syndromeoriginates in the perinatal period?

Chapter 17: Essential fatty acids: biochemistry andPhysiology.

Chapter 18: Role of EFAs/PUFAs in brain growth and developmentand pathophysiology of the metabolic syndrome.

Chapter 19: EFAs/PUFAs and their metabolites in insulinresistance.

Chapter 20: EFAs/PUFAs and atherosclerosis.

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids provides current research exploring the links among insulin, insulin receptors, polyunsaturated fatty acids, brain growth and disease. Specific interactions of essential fatty acids and polyunsaturated fatty acids in brain development and several disease groups are described. The role of inflammation in disease and how fatty acids regulate low-systemic inflammation are examined and explained. Metabolic and neurologic dynamics are presented to provide a linkage between the presence of omega-3 and omega-6 and protection against diseases and conditions such as diabetes mellitus, obesity, autoimmune diseases and hypertension.

Undurti N. Das, M.D. is the Chairman and Research Director
of UND Life Sciences, USA and Ramalingaswami Fellow of the
Department of Biotechnology, India. Dr Das is also the
Editor-in-Chief of the journal Lipids in Health and Disease.
He has published more than 400 international publications and has
been awarded four USA patents.